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Title   인체 위 선암유래 세포주 ( SS-I ) 의 누드 마우스 이식 ( Heterotransplantation of Cell Line ( SS-I ) derived from Human Stomach Adenocarcinoma in Athymic Nude Mice )
Publicationinfo   1984 Jan; 016(02): 229-233.
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Abstract   The result of subcutaneous inoculation of SS-1(Seoul National University, Adenocarcinoma of the Stomach) cell line"' into nude mice is described Three million SS-I cells from passage 29 were injected subcutaneously into the subscapular area of a 57-day-old male nude mouse. But tumor was not produced. Twenty million and one hundred thousand SS-I cells from passage 35-37 were injected into a 27-day-old male nude mouse. After eight days seven million and eight hundred SS-I cells from pasaage 39-40 were injected again into the same site of the mouse. Nineteen days after initial injection: a.tumor became visible at the site of inoculation. After 53 days, the nude mouse died due to wasting by the huge tumor. Sixty-six million SS-I cells from passage 42-45 were injected into a 26-day-old male nude mouae. After 18 days a tumor became visible and it grew fast. After 53 days the tumor measured. 20.8 x 20. 1 x 15.0 mm and the tumot was subpassed to a 21-day-old male nude mouse. After 58days from the first subpassage the.' tumor measured 26. 4 x 22. 4 x 12. 5 mm and the tumor was subpassed again to a 44-day-old male nude mouse. Doubling time of the tumor was about 5.5 days. Histopathalogically the tumors produced in nude mice. were similar to the human tumor of arigin.
저 자   김진복(Jin Pok Kim),박재갑(Jae Gahb Park),양만광(Han Kwang Yang),차창용(Chang Yong Cha),문신용(Shin Yong Moon),김우호(Woo Ho Kim),김용일(Yong Il Kim),장우현(Woo Hyun Chang),이문호(Mun Ho Lee)